In addition to concerts and events throughout the country, JC Hopkins Biggish Band notably played two tribute shows honoring—and featuring—seminal jazz songwriter Mose Allison. The first, in 2001, was held at Joe's Pub in Manhattan and included Hopkins' longtime friend and collaborator, singer Martha Wainwright, Norah Jones, Madeline Peyroux and Queen Esther. One decade later, in 2011, the band held its second tribute to Allison, again featuring the jazz great, as well as his daughter Amy Allison. The performance featured vocalist Elvis Costello performing Allison's songs with the Biggish Band as well as guest appearances by Orange Is the New Black star Lea DeLaria, folk singer Jolie Holland, Verve recording artist Lucy Woodward, and jazz singer Sasha Dobson.
The Biggish Band has also been featured at Lincoln Center's Midsummer Night's Swing and has included songwriter and performance artist Justin Vivian Bond, Joey Arias, Lea DeLaria, as well as jazz pianist and singer Champian Fulton. The band regularly collaborates with various established venues and producers including humorist and writer Kiki Valentine at The Player's Club with Justin Bond, Martha Wainwright, Jolie Holland, The Minsky Sisters, and has appeared at the Blue Note Jazz Festival
In 2014, vocalist Charles Turner joined the ensemble just as JC Hopkins Biggish Band began its Wednesday night residency the legendary Harlem jazz venue formerly known as Minton's Playhouse (now called Minton's Harlem).