Born in Nashville, Leroy Carr moved to Indianapolis as a child. While he was still in his teens, he taught himself how to play piano. Carr quit school in his mid-teens, heading out for a life on the road. For the next few years, he would play piano at various parties and dances in the midwest and south. Carr wandered back toward Indianapolis, where he met guitarist Scrapper Blackwell in 1928. The duo began performing and shortly afterward they were recording for Vocalion, releasing How Long How Long Blues before the year was finished. The song was an instant, surprise hit. For the next seven years, Carr and Blackwell would record a number of classic songs for Vocalion, including Midnight Hour Blues, Blues Before Sunrise, Hurry Down Sunshine, Shady Lane Blues and many others.