Paolo Fresu started studying his instrument at the age of 11 in the Bernardo de Muro music band of Berchidda, where he was born.
After experiences light music he discovered jazz in 1980 and started his professional activity in 1982 following first the and then recording for the RAI, the Italian public broadcasting corporation, (Radio 3 'Un certo discorso) under the direction of Bruno Tommaso.
In 1984 he graduated in Trumpet at the Cagliari Conservatory under Enzo Morandini and attended the music department of DAMS, the faculty of arts of the University of Bologna. Still in 1984 he won several prizes as best talent in Italian Jazz.
In 1990 he won the prize as best Italian musician, best group (the Paolo Fresu Quintet) and best record (Live in Montpellier). In 1996, in Paris he won the prestigious prizes Bobby Jaspar awarded by the Académie du jazz and the Django d'Or (the European music Oscar) as best European jazz musician and in the year 2000 he had another nomination for the Django d'Or as best international musician.
He has been a music teacher in State Middle schools and, for the past twenty years he has led and intense teaching activity in many contexts.
The list of collaborations is prestigious: ranging from the leading Italian musicians like F. D'Andrea, GL. Trovesi, G. Gaslini, E. Rava, B. Tommaso, G. Tommaso, E. Pieranunzi, T. Ghiglioni and others, to Europeans and Americans like K. Wheeler, J. Taylor, D. Liebman, D. Holland, Ph. Woods, A. Romano, G. Mulligan, B. Brookmayer, J. Zorn, R. Del Frà, J. Abercrombie, H. Merril, M. Portal, R. Galliano, T. Gurtu, G. Shuller, M. Waldrom, del Fra, J. Hall, L. Soloff, J. Hassell, Uri Caine, Gil Evans Orchestra etc.